Public Health Surveillance for Adverse Events Following Covid-19 Vaccination in Africa: Rare Adverse Events and Fatal Cases Following COVID-19 Vaccination in Africa

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dc.contributor.authorAnjorin, AbdulAzeez
dc.contributor.authorOdetokun, Ismail
dc.contributor.authorNyandwi, Jean
dc.contributor.authorElnadi, Hager
dc.contributor.authorAwiagah, Kwame
dc.contributor.authorEyedo, Joseph
dc.contributor.authorAbioye, Ajibola
dc.contributor.authorGachara, George
dc.contributor.authorMaisara, Aala
dc.contributor.authorRazouqi, Youssef
dc.contributor.authorMohamed, Yusuf, Mohamud
dc.contributor.authorMhgoob, Zuhal
dc.contributor.authorAjayi, Tunde
dc.contributor.authorNtirenganya, Lazare
dc.contributor.authorSaibu, Morounke
dc.contributor.authorSalako, Babatunde
dc.contributor.authorElelu, Nusirat
dc.contributor.authorWright, Kikelomo
dc.contributor.authorFasina, Folorunsho
dc.contributor.authorMosbah, Rasha
dc.date.accessioned2024-03-25T13:13:06Z
dc.date.available2024-03-25T13:13:06Z
dc.date.issued2022-01-27
dc.description.abstractBackground: The death toll and economic disaster caused by SARS-CoV-2/ COVID-19 is still on the rise globally and in Africa with a case fatality ratio (CFR), 2.58 from 220,958 deaths out of 8,556,890 cases recorded across the continent as of 14th November 2021. Local, national and international health agencies have advocated multi-pronged public health strategies to limit infections and prevent deaths. The availability of a safe and effective vaccine is critical in the control of a pandemic. Several adverse events have been reported globally for different vaccines including COVID-19 with limited or no data from Africa. Methods: This cross-sectional epidemiological study investigated the adverse events following COVID-19 vaccination in Africans between April- June, 2021 using a structured questionnaire distributed via the web for public health surveillance. Results: Out of the 1200 participants recruited, a total of 80.8% (n = 969) respondents from 35 countries including 22 African countries and 13 countries where Africans live in the diaspora reported different adverse events following COVID-19 vaccination. More than half of the vaccinee were male (53.0%) and frontline healthcare workers (55.7%), respectively. A total of 15.6% (n = 151) reported previous exposure to SARS-CoV-2 while about one-fourth, 24.8% (n = 240) reported different underlying health conditions prior to vaccination. Fatal cases were 5.1% (n = 49) while other significant heterogenous events were reported in three categories: very common, common, and uncommon adverse events including enlarged lymph nodes 2.4% (n = 23), menstrual disorder 0.5% (n = 5), and increased libido 0.2% (n = 2). Conclusions: The study provided useful data for concerned authorities and institutions to prepare plans that will address issues related to COVID-19 vaccines.
dc.identifier.doihttps://doi.org/10.14293/111.000/000024.v1
dc.identifier.urihttps://africarxiv.ubuntunet.net/handle/1/1397
dc.identifier.urihttps://doi.org/10.60763/africarxiv/1338
dc.identifier.urihttps://doi.org/10.60763/africarxiv/1338
dc.identifier.urihttps://doi.org/10.60763/africarxiv/1338
dc.language.isoen
dc.subjectVaccine adverse events
dc.subjectSARS-CoV-2
dc.subjectCOVID-19 vaccine
dc.subjectPublic health
dc.subjectVaccination
dc.subjectAdverse events following immunization (AEFI)
dc.titlePublic Health Surveillance for Adverse Events Following Covid-19 Vaccination in Africa: Rare Adverse Events and Fatal Cases Following COVID-19 Vaccination in Africa

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