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Epigenetic Modification In Relation To Some Common Cancers

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dc.contributor.authorAdelola, Oluwatoyosi, Naomi
dc.contributor.authorOlayemi, Rotimi, David
dc.contributor.authorAdedoyin, Owolade, John-Joy
dc.contributor.authorOpeyemi, Oladeru, Fortunate
dc.contributor.authorAdo, Musa, Abba
dc.contributor.authorSheriff, Agbaje, Tunde
dc.contributor.authorSeun, Ibrahim, John
dc.contributor.authorMuinat, Zubair, Fehintola
dc.contributor.authorBello, Ridwan, Opeyemi
dc.contributor.authorAdejo, Oche, Samuel
dc.contributor.authorNwankwo, Daniel, Ogbonnaya
dc.date.accessioned2024-03-15T11:40:27Z
dc.date.available2024-03-15T11:40:27Z
dc.date.issued2022-11-10
dc.description.abstractEpigenetic modification is a process that regulates DNA sequences without altering the original structure of the DNA sequences. The distortion of DNA by epigenetic modification can turn gene expression off or on. Several scientific pieces of evidence have shown that the regular occurrence of a genetic mutation governed by epigenetic changes can subsequently usher in the onset of many diseases, including Cancer. DNA methylation and histone modifications, such as acetylation, methylation, and ubiquitination, which are well known to influence gene expression, are among the most frequent epigenetic changes. In this review, we ostensibly review epigenetic modifications and their relation to cancer development. We observed that many epigenetic changes in gene expression are actively linked to Cancer, and it remains one of the most potential areas in cancer research. Many epigenetic mutations are repeatedly detected in cancer research, and reversing these mutations in cancer cells can lead to the discovery of novel therapeutic approaches and cancer biomarkers.
dc.identifier.doihttps://doi.org/10.31730/osf.io/9q8g6
dc.identifier.urihttps://africarxiv.ubuntunet.net/handle/1/567
dc.identifier.urihttps://doi.org/10.60763/africarxiv/525
dc.identifier.urihttps://doi.org/10.60763/africarxiv/525
dc.identifier.urihttps://doi.org/10.60763/africarxiv/525
dc.subjectCancer
dc.subjectDNA
dc.subjectDNA methylation
dc.subjectEpigenetics
dc.subjectGene
dc.subjectHistone Modification
dc.subjectNon-coding RNA
dc.titleEpigenetic Modification In Relation To Some Common Cancers

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